Artificial intelligence for macromolecular analysis and pharmaceutical ligands design
Objectives: Elucidating the complex structures of biological macromolecules from CryoEM images. Discover ligands that fit into the structures revealed for new drug design. Expected Outcomes: Robust algorithms and workflows to tackle both problems. The problem to address : The journey from pixelated snapshots to precise atomic models is fraught with computational hurdles,
New position open: Software Developer in the Biocomputing Unit (BCU), Instruct Image Processing Center (I2PC), Madrid
Description: We are looking for a candidate with a BSc/MSc in Computer Science, Mathematics, Engineering, Physics or equivalent with software development skills. The candidate will be involved in European and National projects related to cloud and open data technologies, being part of a team in charge of developing data management software for Instruct facilities. Thus,
An asymmetric structure of the Leptospira´s flagellar filament
Date and venue: 2024, February 22th al 10.00 CET. B6 room- CNB/CSIC, Madrid Summary Description:Leptospira species, as all spirochetes, possess specially adapted endoflagella confined within the periplasm. Endoflagella are essential for the fast corkscrew-like swimming and pathogenicity of leptospires. However, little is known about the composition, function, and molecular architecture of these endoflagellar filaments. Through
Structural studies on cyanide degrading nitrilases
Date and venue: 2024, February 15th al 10.00 CET. B6 room – CNB/CSIC Summary Description: Cyanide is widely used in industries due to its high affinity for metals. This characteristic is at the same time responsible for the potent toxicity of this compound. Thus, industries have to reduce the cyanide concentration from wastewater before its
Structural Biology 2.0 : computational tools and X-ray diffraction integrated to solve and understand 3D protein structures
Date and venue: 2025, from April 21 to 30. Institut Pasteur de Montevideo (Uruguay). All invited speakers/tutors and students from abroad will be lodged in the same hotel. Webpage under construction: stay tuned for upcoming information! Summary Description: The workshop will cover theory and hands-on practical work, the latter including tutorials and the students’ own data
I2PC Course on Single Particle Analysis by CryoEM. Madrid, 20 – 22 March, 2024
Venue National Center for Biotechnology (CNB), Madrid, SpainMadrid, March 20 – 22, 2024How to find us: http://i2pc.es/contact-us/ Overall aims and course outline Cryo-Electron Microscopy has established as a mature technique to determine the three-dimensional structure of biological macromolecules. It is currently reaching atomic resolution and it is capable of accessing to the structure of conformationally heterogeneous
I2PC – Instruct-RI Hubs hybrid course on Electron Tomography and Subtomogram Averaging. Madrid, December 10 – 13, 2024
VENUE Hybrid course.December 10 – 13, 2024 from 16:00 to 21:30 CET.You do not need to install any special software to connect. A modern browser should be enough. Overall aims and course outline By using image processing algorithms, it becomes possible to pinpoint the macromolecules of interest within the electron tomograms. Subsequently, researchers can extract
ComulisGlobe Correlative Multimodal Imaging Workshop in Genoa
Date and venue: 2024, 21-22 of March in Genoa. Summary Description: The workshop will include lectures on Light microscopy, Electron microscopy and Atomic Force Microscopy, as well as laboratory demonstrations on various microscopy modalities. A session on correlation of images will also be included. For more information see: https://www.comulis.eu/
Fundamentals of light microscopy and image processing
Date and venue: 2023, 18-29 of September at ITQB-NOVA. Will transmit lectures over Zoom: https://videoconf-colibri.zoom.us/j/95295678533 Summary Description: The course “Fundamentals of light microscopy and image processing” will focus on the application of fluorescence microscopy in molecular and cellular microbiology and infection biology. This course will pass on basic concepts and practical training in conventional epifluorescence and
Position Open in image processing for Cryo-Electron Microscopy at BCU
The Biocomputing Unit (BCU) of the Natl. Center of Biotechnology is looking for a candidate with a background in Engineering, Physics, Mathematics or any other data analysis related field. The work is about the development of image processing in Cryo-Electron Microscopy (CryoEM) with a special emphasis on signal processing and efficient implementations. Our laboratory is
PhD. position in image processing for Cryo-Electron Microscopy
The Biocomputing Unit of the Natl. Center of Biotechnology is looking for excellent master students in Engineering, Physics, Mathematics or any other data analysis related field that can compete for FPU fellowships: (https://www.educacionyfp.gob.es/servicios-al-ciudadano/catalogo/general/99/998758/ficha/998758-2020.html). The Ph.D. would be about the development of deep learning methods for image processing in Cryo-Electron Microscopy. This project involves several quickly
Position Open: Bioinformatician at Biocomputing Unit CNB
The Biocomputing Unit (BCU) of the National Center for Biotechnology, headed by Drs. Jose Maria Carazo and Carlos Oscar Sanchez Sorzano, works in the area of both experimental and computational structural biology, coordinating Spanish efforts in the European Infrastructure for Integrative Structural Biology Instruct-ERIC. We develop new ways to extract and integrate biomedical information with